The Judges cut a 17-point deficit down to just five at the end of the third, but they couldn't quite climb all the way back. Noel Hodges had 10 points in her final game as a Judge.
Rookie Camila Casanueva tied her career-high in scoring, but the Judges were unable to overcome a tough shooting performance in the third as they were outscored 13-5.
The Judges took a brief lead with a 3-pointer to open the final period, but the 'Jackets answered with the game's next nine points to pull away for the win.
Camila Casnueva had 16 points and a career-high eight rebounds, but it wasn't enough to overcome a tough shooting night and an improved performance from the field by the Spartans.
Katie Goncalo outscored the Spartans by herself in the second half en route to a career-high 21 points. The Judges outshot the visitors, 60% to 17% after halftime, and outscored them, 35-14.
Noel Hodges scored eight points in the second quarter and matched her career-high with 13 for the game, but Rochester outscored the Judges 20-11 in the final period.
The Judges carried a 51-49 lead into the final 10 minutes, but the Maroons opened the fourth on a 10-1 run to take the win. Sarah Jaromin scored a team-high 12 points off the bench, while Hannah Nicholson grabbed 16 rebounds.
Danielle Fitzpatrick '04, Jessica Chapin '10, Caitlin Malcolm '07, Jaime Capra '08, and Racheal Perry '92 were honored as members of the UAA's elite team.
The Judges outscored the Bears, 26-11, in the second period and kept the Bears at bay for their first win over WashU since 2008 and their first in the Arch City since 2005.
The Judges never trailed as they got off to their best start since 2014-15 headed into UAA play on Saturday. Jillian Petrie had 11 points for Brandeis.
Kat Puda scored a career-high 15 points, including four of the team's 11 3-pointers, their most in a game since 2009. The Judges also doubled up the Gulls on the glass, 54-27.